Two first pair guanidine manages the 2 type diabetic result and demands urgently to optimize Chinese scholar will carry on large-scale clinical research independently

Two first pair guanidine manages the 2 type diabetic result and demands urgently to optimize Chinese scholar will carry on large-scale clinical research independently
It is reported ' Reporter Wang Dan) As to 2 type diabetic in China, when first pair guanidine form medicine treatment of China's low dosage two is not up to standard of, the increase dosage or which scheme of the union administration is more rational? What is launched independently for the first time by the Chinese scholar in order to answer the above-mentioned problem is called " VISION " on a large most scale Diabeteses 2 type contrast at random and last clinical research a few days ago to start formally. The intersection of research and chief leading cadre, the intersection of Chinese Medical Association and diabetic credit this know the intersection of General Board and discipline, stand agricultural Professor, say, two first guanidine 2 type the intersection of first-selection and therapeutic medicine of diabetic at present, until " whether China 2 type diabetes prevents and cures the guide " The requirement, for instance, the patient does not have taboo disease, two first pair guanidine should be keeping in the healing solution all the time. But in clinic, when two first pair guanidine is used invalid, continue strengthening the dosage, jointly treat and change to many medicines, what the opportunity changed is, all lack and follow the medical research evidence of the card, the doctor often judges according to the personal experience, cause the therapeutic effect to be non- good. Study to reveal, two first pair guanidine form medicine is employing for 6 months to begin to rise promptly blood glucose after one year, increase the single medicine amount simply, the bad reaction will thereupon increase, curative effect, but without the obvious change. According to oral drug therapy mode investigation of 2 type diabetes of the whole country of 2011, interview in the patient in 9872, 10.7% people adopt two the intersection of first and the intersection of guanidine and the intersection of form and the intersection of medicine and treatment, 33.5% people adopt two the intersection of first pair and jointly treating based on the guanidine, but whole and saccharified getting up to standard hemoglobin ' < 6.5%) It is only 28%. This data brief on on one hand, two first pair guanidine is employed as 2 type diabetes first-selected therapeutic medicine and basic administration united in the scheme still insufficient at present, on the other hand with lower the intersection of candy and medicine such as the intersection of sulphur and urea while being existing / dose list person who endure to be in not treating jointly easy to cause hypoglycemia and weight increase, thus influence the patient to treat tolerance and complying with and make curative effect limited and relevant. It is introduced, this " VISION " Research will be launched in 115 clinical research centers of the whole country, plan to enter 3312 group's patients. Among them, 2760 patient low the intersection of dosage and two the intersection of first and guanidine unite with lower candy medicine, link Georgia and list the spit of fland to treat while being new in the use, 552 patients adopt two first pair guanidine of maximum dose to treat.

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