1/5 of the old men suffer from nephropathy It is easy to be ignored for symptom to hide
Find in the physical examination of the health, the elderly suffer from various renal patients are up to 17.3%. According to the statistics of old and feeble branch of U.S.A. NIH, are dropping in several kinds of highest disease morbidity such as heart disease, tumour of U.S.A.'s fatality rates year by year, but morbidity such as chronic kidney trouble rise year by year, especially the morbidity of old crowd's chronic kidney trouble obviously rises, 11% suffer from above- 3rd -class chronic kidney trouble in the crowd over 65, most above- 3rd -class patients will develop to uremia. So, aging population is in close relation with old kidney trouble. Kidney old and feeble to influence obvious organ most one of, it is function that fail fast organ most one of too. The old and feeble very fast normal people of the elderly's kidney, with the years 30 years old later the same, the renal size, weight are lightened gradually, the weight can be reduced from 150-200g at the age of 30 to 90 -year-old 110-150g, can reduce 30-40% when the renal volume is younger at the age of 90; Since 50 years old, probably every 10 years, the volume is reduced by 10%. Can observe the elderly's nephron quantity is reduced, the volume is reduced on histology; By about 80 years old, the nephron is reduced from 1 million to about 600,000. In function of the glomerulus, 30 to 40 years old later, renal blood flow is reduced at the speed of 1% per year, glomerular filtration rate is reduced; 80 years old later, the renal function will lose 30~40%, and will generally have white proteinuria of trace. Because medicine and supersession product are mainly discharged by the kidney, and the excretion of medicine is closely related to glomerular filtration rate. Renal functions of old person fail to enable absorbing to the medicine of organism, transshipping, distribution, supersession and excreting,etc. different from young people, the more medicine kinds used are, the higher the incidence of the side effect is. So someone propose patient over the 50, every the intersection of increase and a year old, the medicine dosage should be reduced by 1%. Old kidney trouble is more concealed on one hand the old patient is wrong displays nephropathy and is regarded as the normal aging phenomenon by mistake, do not pay attention to, typicality neglect, have illness coming on originally because of disease on the other hand if hypertension, high the intersection of lipoprotein and the intersection of blood and disease, diabetes, high the intersection of urine and the intersection of acidaemia,etc. and impact on kidney. The clinical manifestation of the old kidney trouble is different from young people, nephropathy and syndrome are the common behavior of the elderly's kidney trouble. Low albumen blood disease is often very prominent, more chances hypertension, renal function take place and fail. There is no urine examination of symptom to unusually account for 20%, because symptom is hidden, if irregular physical examination, these symptoms are often easy to be ignored.
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