First a first type H1N1 influenza virus in Beijing has not made a variation greatly

First a first type H1N1 influenza virus in Beijing has not made a variation greatly
It is reported ' Reporter Tan Jia) On May 20, the whole genome array of first first type H1N1 influenza virus of Beijing is succeeded in determining. Check order result brief on, first type H1N1 still relatively steady the present stage in influenza virus, have great variation; The virus is still right to reach neural amino acid enzyme inhibitor such as Philippines to be sensitive. Etiology biological researcher of research institute and institute of lab animals of Chinese Academy of Medical Sciences of the Chinese Academy of Medical Sciences, the northern research center personnel of Beijing Municipal Center for Disease Control and Prevention, national human genome work in concert, fight bravely continuously through 30 hours, utilize the first type H1N1 influenza case (the third of hinterland of our country) Swallowing the swab sample finishes determining. Compare, researchers find a high homology of first type H1N1 influenza virus separated with U.S.A. of this virus through array analysis, compare with representative of U.S.A. prototype of A/California/04/2009, hemagglutinin (HA) The genetic nucleotide homology is 99.76%, the amino acid homology can be up to 99.47%; Neural amino acid enzyme (NA) The genetic nucleotide homology is 99.86%, the amino acid homology is up to 100%. It briefs first type H1N1 on to be still relatively steady in the present stage after travelling in crowd in influenza virus, do not have great variation. The result reveals too, first type H1N1 influenza virus is right to reach neural amino acid enzyme inhibitor such as Philippines to be sensitive to check order. Making offering the important basis for formulation of the tactics of prevention and control of recent first type H1N1 influenza of these results. The whole genome array is that the scientific research personnel utilize patient's primitive sample to determine and get arrays after amplifying the gene directly, have not separated and trained the virus, has avoided the variation that the virus takes place in external cultivation, so can reflect the truth of the virus in the human body is infected with even more.

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