The mankind gives a birth and starts the mechanism to study and obtain progress

The mankind gives a birth and starts the mechanism to study and obtain progress
It is reported ' Reporter Sun GuoGen) Recently, Fudan University university student order scientific the intersection of institute and one mankind of seminar, Professor of Gang, Sun give a birth, start mechanism, study, cause the people of the same trade at home and abroad pay close attention to the fact. Discover, in later period for human gestation, internal glucocorticoid not merely promotes the maturity of foetus' organ, and can promote the fetal membrane to organize the formation of prostaglandin. Function is very clear in glucocorticoid is in most mammalian childbirths are started. Participate in giving birth to prostaglandin starting to mainly come from the fetal membrane, but the function mechanism in the mankind gives a birth and starts of glucocorticoid has not been bright. The seminar employs the main cell type amnion of synthetic prostaglandin of people's fetal membrane to become fibrous cells, adopt the real-time quantitative polymerase chain and react (PCR) , albumen blot hybridize and gene start the intersection of son and clone and mutation, the intersection of chromatin and the intersection of immunity and the intersection of precipitate and immune coprecipitation,etc. and technology, analyze glucocorticoid induce the intersection of people and the intersection of fetal membrane and molecular mechanism that prostaglandin formate. Discover in the regenerative cycle turned into, a kind of glucocorticoid exists in the fetal membrane, the forming of this cycle, it is to lead glucocorticoid to raise one kind and activate enzyme to express and finish by oneself by a transcription factor in the human body, and glucocorticoid that is producing constantly has induced the increasing synthetically and constantly of prostaglandin of fetal membrane, cause the start giving a birth finally. Study yet to further find, progestogen is to maintain pregnant key hormone, and progestogen and their the intersection of receptor and A can weaken glucocorticoid, induce the intersection of people and amnion become fibrous the intersection of cell and two the intersection of prostaglandin and synthetic normal expression of enzyme these while being getting inferior, the weakening to compete with glucocorticoid receptor and inhibit the glucocorticoid receptor from duplicating the activation to realize through progestogen separately in function. Regenerative cycle that this research results have verified glucocorticoid of fetal membrane for the mankind for the first time and prostaglandin turns into, in order to develop new medicine Israel in the future " Stop " Give a birth and start the regenerative cycle that the son hit prostaglandin and turned into, prevent and cure premature delivery to offer the new thinking. Relevant serial thesis issue in latest the intersection of U.S.A. and clinical endocrine with the intersection of supersession and magazine, the intersection of endocrinology and magazine,etc., member of American, at the international authoritative periodical already, the result of study is also recommended to reader by the American molecule endocrinology magazine and light spot of medical research in order to transform of American doctor's network, and the annual meeting of American gynaecology and obstetrics is selected as speech 2011.

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