People's skin cells are turned into the nerve cell by directness for the first time

People's skin cells are turned into the nerve cell by directness for the first time
According to the report of Washington (Xinhua) the 4th August ' Reporter Ren HaiJun) The researchers of Columbia University of American say on the 4th, they wound stem cell stage, turn human skin cells into the normal forebrain nerve cell of function directly for the first time. Relevant research results are published on " cell " magazine network edition on the same day. The eighties began since last century, the scientist had already realized, all-round (can divide into all different types of body cells) And the embryo stem cell that can be repaired oneself will be regenerating the medical field and playing an important role. However, because draw embryo's stem cell and involve the ethics problem, the scientists begin to look for and substitute the method. In 2007, scientific circles makes the break-through in this field - -American and Japanese scientist turn ordinary skin cells into inducing the multi-functional stem cell respectively, the latter has it with embryo's stem cell's similar function, but get around the ethics obstacle brought in embryo's stem-cell research, inducing the multi-functional stem cell therefore becomes one of the hot fields of stem-cell research in recent years. However, induce the multi-functional stem cell's shortcoming to be very prominent: Difficult to obtain, transform time longer and initiating the risk of cancer. In 2010, the researchers of the medical college of Stanford University are around inducing this step of the multi-functional stem cell, will test mouse's skin cells to turn into the nerve cell directly for the first time. On the basis of studying in Stanford University, associate professor of Columbia University medical center A Abe and Leo Sa linked the group led very to use different transcription factor associations, and added the nerve cell and supported the factor and turned the human skin stem cell into the forebrain nerve cell directly finally. The nerve cell transformed out is the same as normal nerve cell, can send and receive signals behind planting the experimental mouse's central nervous system into. Abe and Leo links very and says, this research is still at early stage, has not done a good job of the preparation of clinical practice yet, but the new achievement gives and treats Alzheimer's neural regression diseases such as disease,etc. to bring the new thinking.

|