Directly hematopoietic law of the human skin comes out

Directly hematopoietic law of the human skin comes out
According to the report of Beijing (Xinhua) the 8th November Canadian researchers developed a new hematopoietic method a few days ago, can change the human skin into the blood directly. Medical science this break through, might bring the new blood source with the blood in treatment of cancer and patient's surgery course. MacMaste, researcher of the university of Canada, delivers a report saying on the British Nature network edition, hematopoietic law of the previous skin needs through inducing this intermediate link of the multi-functional stem cell, the new method that and they develop is transforming directly, not only the course is simple, but also the blood quality received is higher. It is introduced, researchers utilize virus to plant into calling the gene of OCT4 in human skin cells, then train in the special environment with many kinds of cell factors. In this way, skin cells can turn into the forebody cells of blood cells directly, cells of these forebodies can produce leucocyte, erythrocyte, 3 kinds of main blood cells of blood platelet. Researchers carry on the above-mentioned experiment repeatedly with adult's skin and neonatal foreskin during two years, verify the skin of the person of any age can be turned into the blood, and the blood function is normal. Once studied and turned skin cells into blood cells too in the past, but the course turned the skin stem cell into inducing the multi-functional stem cell first, induce multi-functional stem cell turn the intersection of blood and cell into and then, getting many to induce multi-functional the intersection of stem cell and these intermediate link. Researchers say, ferroheme function in the blood cells that the indirect hematopoietic law gets is not complete, it is here to still stay " The embryo " But not " Become body " At stage, and that transformed the blood cells got and contained directly is to become ferroheme of body. In addition, often have a risk which cause cancer tumour through blood cells inducing the multi-functional stem cell to get, and will transform the blood cells got to inject into the experimental mouse in the body, has not found the sign of tumour directly. Researchers think, the medical use of this new technology has a bright future. Some patients may not in order to look for matching the blood source to worry, because utilize one's own skin and get necessary blood in the future. Responsible for this research Mick inferior to say profit from this achievement will the intersection of leukemia and patient at first Barry have. They need to transplant the bone marrow with hematopoietic stem cell frequently, but because often accept radiotherapy, its stem cell may morph like cancer cell, but the bone marrow from donor is apt to cause arranging the different response. Any genetic mutation will not take place in skin cells, so can make blood with patient's own skin cells, transplant into patient's body again. Researchers say too, though every experiment in the laboratory reveals now, these artificial blood cells have normal functions, it is done but be really used in there is a lot of work clinicallying.

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