Human sperm's family's first systematic revealed secrets of ripe albumen

Human sperm's family's first systematic revealed secrets of ripe albumen
It is reported ' Special correspondent Li Cheng repairs) The research center of the engineering of stem cell of Shandong, semi-annular jade pendant of Yu of Yantai carry the research group that hospital, Yantai university far professor Li Jian led, through the concentrating on studies of ten years, make the great breakthrough in the human sperm becomes familiar relevant albumen research, research results this " whether molecule and the intersection of cell and the intersection of protein and group study " the intersection of magazine and 2010 11 issues and issue online on December 22, 2010 the intersection of U.S.A. and internationally famous academic the intersection of periodical and MCP continuously. It is the important links that man sexual reproduction is adjusted and controlled that the human sperm is ripe. The sperm produced in the testis, manage a of microenvironment and epididymis and secrete albumens and interact and reach maturity through the epididymis, establish the foundation that the subsequent one is fertilized. Sperm's ripe obstacle is one of the main reasons causing men to be sterile. So, it contributes to improving the clinical and sterile molecule and diagnosing and treating competence as the familiar relevant albumen to study sperms. In addition, it is ripe to interfere with sperms, can also adjust and control reproduction and practise contraception effectively. Li Jian studies the group and regards innovating in source as the starting point far, adopts the engineered molecule biological study means of the system, on the basis of succeeding in analyzing normal epididymis gene expression tables of people, have analyzed human epididymis, testis protein and expressed the table, the epididymis is in charge of the secreting albumen table of a of liquid, and set up 1030 kinds of corresponding protein antibody storehouses, determine, find epididymis and sperm that testis expresses orient 317 kinds of albumens ' Include people's epididymis and secrete the family of conjugated proteln of sperm) ,Have carried on classifying the serial number and naming of scientific system to it, and register and organize the gene pool (GenBank) to the international mankind . Through relevant important target albumens of function such as function discovering and sperm moving, wearing the ovum, can obtain, anti-oxidant and immune defence, human sperms set up become the biological information database of familiar relevant albumen, open to world through the network, has realized the resource-sharing of information. This achievement is organized the domestic expert's evaluation committee to appraise on December 20 of 2009 by the scientific and technological drawing room of Shandong, think that has original, advance, science and practicability, reach the international leading level. MCP evaluation expert and internationally famous man sexual reproduction domain scientist TrevorG.COOPER think, this research has shown normal people's epididymis, testis protein group completely, human sperm become familiar relevant albumen the intersection of revealed secrets and creation of system most in family in the world so far.

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