It is determined by the fact that genetic that Iraq sets up and suffers from diarrhoea the incidence for the health

It is determined by the fact that genetic that Iraq sets up and suffers from diarrhoea the incidence for the health
It is reported whether the Chinese large intestine cancer patient is that applicable Iraq sets up the clinical research of uniting Fluorine urea pyrimidine chemotherapy scheme for the health and makes important progress recently. PLA man discover suitable to set up large intestine cancer patient to take the place of the health with Iraq while being clinical by 307 hospital the intersection of digestive tract and JianMing Xu, head of the department of tumour. This research has offered scientific basis for the fact that the patient used Iraq to set up to the chemotherapy scheme of the health rationally. Iraq sets up and is used for treating two main chemotherapy schemes of large intestine cancer in later period clinically at present for health and inferior calcium folic acid. However, because report abroad Iraq sets up the taking place diarrhoea incidence is relatively high late for the health, there are too many to dare to use domestic clinicians. To question this, JianMing Xu the intersection of gene and many attitude and they, UGT1A of people, and Iraq set up analyze for the intersection of health and toxic relation to the intersection of Chinese and the intersection of large intestine and the intersection of cancer and patient and health. He chooses 100 healthy volunteer and 70 large intestine cancer patients as the research object, probability and big of side reaction of finding Chinese set up with Iraq in order to present after the health, it is not so tall as westerners. Research verifies, it is about 5% that the Hans set up the incidence of taking the place of the side reaction of the health with Iraq, obviously lower than about 20% of diarrhoea incidence of the western report. Xu JianMing finds, being distributed UGT1A enzyme with corresponding more genotypes in the Chinese crowd is relatively high under study for action, this may lead to the fact toxicity reflects the incidence is relatively low among the crowds. Chinese variation distribution situation and American-European report are different, this may be Chinese with the main reason that he set up and suffer from diarrhoea the incidence obviously on the low side for the health. Xu JianMing reminds, before setting up and taking the place of the health medicine to cancer patient of large intestine with Iraq, should find first whether the patient UGT1A gene has made a variation, the possibility substantially as making a variation to suffer from diarrhoea is relatively great, the doctor will do a good job of corresponding aid and treat preparation soon; If has not made a variation, the possibility suffering from diarrhoea is very small. (Zhang Guoqing)

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