It is verified that human cells can duplicate RNA head directly too
The technology that researchers utilize the single member of a kind of quantization to check order recently, detect a new small molecule RNA (ribonucleic acid) in human cells ,It represents a brand-new kind to duplicate the respect in the gene, and verify a kind of assumption for a long time, mammalian cells can formate RNA by duplicating RNA molecule directly. This research is gone on together by medical college, Switzerland Geneva university medical college and two biological scientific technical corporations of University of Pittsburgh, the relevant thesis is issued on latest Nature. This proves human cells can duplicate RNA as duplicating DNA for the first time. Pittsburgh university medical college calculates to say with systematic biology teaching, thesis co-author Beno Dr. John, this discovery has emphasized the variety of RNA colony in human cells, these new RNA, for opening up and treating the new route, especially significant for development of diagnostics. The scientists think for a long time, all RNA in human cells duplicates from DNA mask works, the past record reveals, the duplication mechanism from RNA to RNA observed newly this time, only exist in plant and simple organic matter such as yeast, with a kind of RNA dependence RNA polymerase (abbreviated as RdRP) by name Relevant, this kind of enzyme participates in the critical cell regulatory process. Discover this time, there are thousands of kinds of small-scale RNA that can be duplicated in human cells directly, but this, these RNA, has not been paid attention to. In putting these small-scale RNA in human cells and the tissue in order and sorting out, researchers have also found the new kind of some RNA, including resisting the relevant short chain RNA duplicated, it may be a kind of protein code gene not clear isolated from messenger ribonucleic acid, its RNA duplicates the mechanism on the battle line of human cancer cell ubiquitously. This kind encode the intersection of RNA and member, ignore, because order-checking in the past platform very much difficult to offer accurate quantization to determine only. Helicos biological seat of honor scientific and technological officer Padraic Sri Lankan Dr. Miro of scientific technical corporation thinks, the single member checks order to analyze in the accurate and extensive genetic procedure the respect has important function, also provided the facility for clinical practice.
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