Protein a group of research of human liver plans to obtain important progress

Protein a group of research of human liver plans to obtain important progress
It is reported ' Special correspondent Wu ZhiJun flies in reporter's Shenyang base) Recently, good news comes in the research center of group of protein of Beijing, have praised as " nine major planets " "Liang table" , " two pictures " , " two groups " , " three storehouses " The task, namely express the table and modify the table, orient picture and chain picture in the human liver protein group, physiological group and pathologic group, sample storehouse, antibody storehouse and database, are explored by the scientist hardships for more than 5 years of our country, the basic framework has already been finished at present. Originally, academician He FuChu suggested establishing " the human liver protein group study the plan " at the international conference When, that expected is to look for and treat " gold key " of hepatopathy for this hepatitis big country of ours . In the 5 year, Beijing the intersection of protein and the intersection of group and research center succeed in, appraise human the intersection of liver and more than 13000 of protein; Construct the largest scale in the world, contain more than 3480 to the high network chart that can believe liver protein interaction; Have set up the human organ protein group's database of first system in the world; Have found fatty liver, hepatocyte virus infecting, canceration and shifting relevant protein mark group, potential medicine target and drug candidate; Have found a batch of exchanging the sense gene correlated to complicated diseases such as hepatocarcinoma, pyemiapyaemia and nasopharyngeal carcinoma,etc.. From 2005 to September of 2010, this centre published 230 scientific papers together, influenced the factor to total 1307. Among them, publish 11 articles in international top publication " Nature " serial sub publications, " science ". Obtain the above 11 achievements at provincial and ministerial levels such as second prize of National Prize for Natural in Sciences, second prize of National Prize for Progress in Science and Technology, first prize of the military progress prize in science and technology.

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