The genetic DNA password of intestinal fungus of the human body is totally analysed and explained
Control the mystery of health or illness " The key " ,Does not only grasp in the genetic hands of mankind itself, the microbial gene in the human body may " wield the sceptre " too . Yesterday, " European Union - China's High-tech Industries Week " Release the scientific research collaborative project of the star that more than 30 Europe and China scientific research group participate in together. Among them, visiting professor of Denmark Copenhagen university, the intersection of China and loud genetic the intersection of executive president and Wang Jun Professor have brought the latest news that human Acer learns to be studied because of the group: Human body's intestinal fungus has 3 million to 5 million genes in all, its DNA password has already been totally analysed and explained. At present, researchers are judging every genetic function, and the role acted at different diseases. Because the group receives much concern if concentrates the birth course of the life on earth into one year in Acer, the mankind is " The last second " Thing,but appear microorganism it is here "first second " . So, will understand human biology in detail and not merely need to know the human genome, need to have very good understanding to human microorganism's Acer because of the group even more. The mankind always lives together with the microorganism existing in the environment, health even cell. The quantity of the microorganism is more than ten times of the cell quantity of body in the human body, its genetic code is 100 times of human genome even more. These complicated, dynamic microorganisms have important influence on human physiology, nutrition and immunity, the disorder of human body's little biocoene is a main factor which cause disease. Understand trends and essence of human body's little biocoene for changing, it is an enormous scientific challenge; Define such dynamic variety, has opened up the brand-new development field for genomics. In order to finish this goal, researchers focus on the intestinal microorganism group having an important effect on health at first. The seventh frame agreement of European Union has been put into the subsidy of 11,400,000 euro " Human intestinal Acer is because of group's plan " ,The big gene of China of our country is that the only one is not European Union research institution in the participant, also the only person who is selected at home. Is it thin that one group of decisions of intestinal fungus is fat? "The human intestine have 1000 to 2000 kinds microorganism in all, a group of total weight of the fungus is one or two kilograms. " Wang Jun says, this project studied and already entered the third year, found finally, the intestinal bacterium had more than 3 million genes in all, far go beyond more than 20,000 genes of mankind itself. These genes are belonged to different bacteria of 1000 multi-type respectively, have at least 100 multi-type bacteria among them in everybody's intestine. About 40% of the bacteria can find in the intestine of half the number research object. A lot of bacteria are beneficial in the intestine, they help the human body to deal with complicated compound, can also produce amino acid and vitamin, intestinal kind and quantity and healthy to have close relations of bacterium. At present, all the intersection of intestine and microbial gene check order, finish already, through check order deeply and various experiment, define and describe intestinal Acer confirms it and relation between various diseases because of group's function. For example, have some microorganisms in fat people's intestine, but not have in the thin human body. In the experiment, researchers plant some fungus groups in the fat mouse's intestine into the thin mouse's body, the thin mouse will be getting fat. "In life, some people are not fat no matter how to eat, some fat that some people eat, besides one's own genetic decision, and an important factor - -Intestinal fungus group. " Wang Jun explains, if you like eating the meat, that microorganism in the stomach will like eating the meat, finish digesting the meat, will " eat " The intestines wall, the ones that have strengthened the intestine are penetrating on one hand, on the other hand may even bring the fat. Meanwhile, researchers are still relation between studying diabetes and intestinal microorganism. Divide into groups and contrast the experiment to reveal, really have two kinds of characterized microorganisms in the diabetes patient's intestine, "these two kinds of microorganisms are pathogenic reasons of diabetes, or the result of development of diabetic course of disease, still need to further study. " (reporter would rather inferior horse the intersection of intern and neat brilliance of the rising sun have)
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