Tuesday, March 20, 2012

Watch diabetes to study progress from four major rewards

Watch diabetes to study progress from four major rewards
The diabetic centre of BJ Union Hospital resembles Xinhua to red man The 44th Europe diabetes study the annual meeting ( 44thEASD) Held in Rome, capital of Italy in September. People are easy to find a lot of light spots of 44thEASD are becoming topics that the diabetic circle personage is dwelling upon with great relish, and will influence the future of the international diabetic circle. 44thEASD meeting content involves every aspect of diabetes and complication, refers to essence, benevolence person sees benevolence, the wise meet intelligently. In lecturing and four major rewards that we want to talk about this opening ceremony of the conference here, and we understand, some contents paid close attention to. Ricordi professor of American Miami University has introduced the newest progress that the Langerhans' islits is transplanted exhaustively on the opening ceremony who will win the laurel of four major rewards. Ricordi whether world-famous cell transplant, study house in Professor, he say the intersection of people and Langerhans' islits separate the technical article to issue so far automatically from 1986, in more than 50 medical research centers of the whole world, more than 700 patients have accepted already the Langerhans' islits is transplanted and treated, the research of transplanting correlation technique, treatment medicine and curative effect and security of Langerhans' islits develops fast. Expect we in shortly after future,be lasted diabeticed, especially the 1 type diabetic radically treats one of the means. After obtaining Banting award at ADA annual meeting this year, the professor of Texas university DeFronzo of U.S.A. has obtained ClaudeBernard award that this EASD annual meeting awards. It is used for rewarding and made to the remarkable contributor in diabetes and relevant supersession academic progress of domain of disease that ClaudeBernard rewards. This year, with their until insulin resist and lipoprotein toxicity associated with coronary heart disease the research of the respect obtain this special honours the intersection of DeFronzo and Professor. CastelliPedroli award used for rewarding and organizing pathology, having illness coming on to study and preventing and curing the researcher who is made remarkable contribution of the field at diabetes. Winner of this reward of this year is Avogaro professor of Italy. In the speech, he points out the leather grandfather's cell quantity reducing and damaged phenomenon of function while storing in in the 2 type diabetic's body, this kind of phenomenon and atherosclerosis blood vessel incident increase dangerously relevantly. Minkowski reward authorize under the age of 45 to inhabit researcher in Europe for a long time mainly, regard rewarding it as the intersection of diabetes and relevant research and outstanding contributions that progress make. This year, the research institute Br of science of heredity of Germany Cologne university Ning becomes winner of this award, it is a insulinogenic role in central nervous system that it obtains the award and studies. It is AlbertRenold award finally. This reward was set up in November of 2006, mainly rewarded and made to the remarkable contributor in the Langerhans' islits research field. Henquin professor of Belgium obtained this award because of the potassium ionophore finding ATP sensitive. He points out this kind of potassium ionophore is playing a very important role in ��'s cells of Langerhans' islits, and it is a pair of phases, concepts controlled to put forward the trigger of the Langerhans' islits ��'s cell secretion function and enlarge the course in grades. UKPDS follows the trail of the result in ten years Another great content that we pay close attention to is it is studied (UKPDS) that British diabetes is prospective Anaphase track test. UKPDS studies and starts to be lasted 20 years to examine the research that the 2 type diabetic carried on to 5102 newly by 23 medical centres in Britain in 1977, whether could reduce or delay emergence and development of diabetes and chronic complication to control to canvass blood glucose and blood pressure in its purpose, and lower the pros and cons of the candy medicine. Deliver 34 sessions of Europe diabetes held to Barcelona to 1998 and learn the annual meeting in result of study, it happens that 10 years are that diabetes treats a milestone achievement in study history so far, follow-up study is constant so far. The follow-up track test include to all existence patients in 10 - year long monitoring ' 1997~2007 years) ,Researcher go on, follow up a case by regular visits to to experimenter every year, follow up a case by regular visits to for clinic the past 5 years, the next 5 years follow up a case by regular visits to for questionnaire, it is 17 years to follow up a case by regular visits to the median wholly. HbA1c level, observe and intervene the scheme that blood glucose controls after the test stops after the test stops to follow up a case by regular visits to the content and include observing intervening, appraise early blood glucose, blood pressure and intervene the long-term influence on blood capillary and trunk incident, and evaluate health economics. Track on later stage the experimental result shows, though the difference that early blood glucose controlled has already disappeared, but is tried the 2 type diabetic's blood capillary pathological change risk, sent the risk of the heart stem newly, and the whole risk that dies is still reduced continuously. That is to say, it is still obvious that early diabetes strengthens the therapeutic benefit. But after controlling the difference to disappear in two groups of blood pressure, the income that blood pressure controls be unable to last before. The patient proving 2 type diabetes and amalgamating hypertension improves blood pressure and controls the risk that can reduce complication in early period, but if maintaining this kind of income must keep blood pressure controlling well continuously. VADT follow up a case by regular visits to, fruit at the meeting this announcing another item prospective to contrast, test at random also newly and whom VADT study follow up a case by regular visits to the result newly, the research is while controlling hypertension, hyperlipemia,etc. cardiovascular dangerous factor, relatively strengthen and lower candies and lower candies to the influence of one and other complications of running affairs of 2 type diabetic's energies conventionally. Since starting in 2000, VADT studied to include in 1791 2 type diabetics in U.S.A. altogether, patient the mean age is 60 years old enter group, 11.5 years such as course of disease on average, the base-line HbA1c level 9.4% on average, most patients, with cardiovascular complication or dangerous factor. Average for 6 years after following up a case by regular visits to period, it is 8.4% to treat the group HbA1c conventionally, strengthen and treat the group to drop to 6.9%. Two groups of blood pressure and fat of blood have reached and controlled well, there is no prominent difference. Make people feel what some do not understand is, similar to earlier ACCORD research that announce of this year, strengthen, lower candy group piece compound terminal and all because of the intersection of mortality and with treat group, compare, have prominent difference conventionally in run affairs by main energies, and strengthen and treat group's hypoglycemia incident prominently more than the regular treatment. UKPDS tracks on later stage the experiment and VADT result of study are prominent to strengthen and lower the importance of the candy in early days, lower candies strictly as soon as possible, can benefit for a long time. The research proposed the elderly especially long patient who has already had many kinds of cardiovascular complications of course of disease and strengthened and treated the problem that has been worth recommending too at the same time. Its conclusion happens to coincide with our views, that is for old diabetic, should grasp " stop before going too far and have too much of a good thing " to control in blood pressure, blood glucose and fat of blood Principle. EDIC Subsequent result of study In the diabetic domain another one is milestone are studied - -Diabetes is controlled and tested (DCCT) with complication When finish, the researcher decides to follow up a case by regular visits to the patient, carry on EDIC test. 97% of DCCT experimenters participate in the observing of EDIC, does not divide and strengthen treating and regular treatment again, all encourage strengthening and treating, in order to find out about trunk pathological change and rule of development of pathological change of the blood capillary. The result shows: There is supersession memory at diabetes in early days, if lack the good supersession to control, the change will accumulate gradually, become irreversible to damage finally; If improve the supersession to control as soon as possible, can lighten the accumulation of the shouldering change. It is easy to find out, it is to strengthen the key point lowering candies and succeeding that the enlightenment that we receive again from it is intervened in early days, blood glucose is controlled should begin as soon as possible, can benefit for a long time in this way. In addition, 44thEASD has many light spots too, such as the clinical diabetic albumen group learns to study, 1 type diabetes have illness coming on mechanism study, the intersection of glutaminic acid and the intersection of decarboxylase and antibody and the intersection of diabetes and relation research of dividing into type, the regenerated research of ��'s cell of Langerhans' islits, insulin is studied on the function of the central nervous system, new oral administration lower the intersection of candy and medicine and insulinogenic clinical research, whom insulin treat send children fat relevant factor analysis under diabetic while being new, prevent and cure progress of ulcer of diabetic foot,etc..

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