Wednesday, March 21, 2012

Why can human cells " Each performs its own functions "

Why can human cells " Each performs its own functions "
It is reported ' Reporter Hu DeRong) The research of a methyl mechanism of going about DNA, has found the 7th kind of decoration base. The expert thinks, this research knows animals and plants growing, emergence of the disease of animals and plants to develop to the mankind, split up ripe body cells against changing into stem cell,etc., have very important meanings already. This research is good by biochemistry of research institute of Shanghai life of Chinese Academy of Sciences and biological the Xu 's of research institute of cell,etc. scientific research personnel finish, the relevant thesis is issued on latest Science online recently. It is introduced methyl whether protein and the intersection of core and an sour kind decorate importantly, can regulate the expression of the gene and close, grow with the animals and plants, it have close relations that development takes place in the disease. DNA methyl can close the activity of some genes, go methyl induce the activating and expressing anotherly of the gene. There are 4 kinds of common base forms, namely adenine (A) in the higher and biological genome DNA , guanine (G) , thymine (T) With cytosine (C) . Besides this, existing research also finds that there is the 5th kind of base that exists - -5 - methyl cytosine ( 5mC) . And the 5th kind of base is further oxidized as 5 - hydroxyl cytosine ( 5hmC) ,Become the 6th base. Whether outside the body or in the cells that is trained, the 5th base and the 6th base in DNA can all be added oxygen enzyme and further oxidized for 5 - carboxyl cytosine, this has presented the 7th kind of base. Scientific research personnel find, the 7th kind of base, this new base, decorates the form under study for action, can be recognised specifically by candy glucoside enzyme cells, and excise it from genome, and then replace one of DNA four major common bases in order to be decorated - -Cytosine (C) . This finds that has gone to methylation and physiological function to point out the direction in order to study DNA, can used for what cell in the human body's different histoorgans does it explain, though include the same hereditary information, but will exercise different functions.

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