Russia finds stem cell's treatment is ischemic and effective to the chronic lower extremities

Russia finds stem cell's treatment is ischemic and effective to the chronic lower extremities
Moscow, September 7 (Xinhuanet), deal with diabetes or treatment which is short of blood of lower extremities that atherosclerosis causes, mainly have drug therapy and blood vessel by-pass surgery at present. Whether could use on this basis " The cell treatment " Let the intersection of disease and blood vessel regeneration of position, thus resume blood flow volume? Russian researchers treated the experiment and made the positive result to the big mouse with the stem cell not long ago. Russia " The base Roth " Military medical institute expert say at " cells are transplanted with the organizational project " in a new Russia academic publication, they carry on the ligature of artery on the thigh of the large mouse, ischemic main symptom of the chronic lower extremities appears in simulation. Then, from " close relative " of the big ill mouse It draw on bone marrow at organism monocyte,at these cell include not lasting blood celling and among quality stem cell. After transplanting the above-mentioned cells to the disease position of the large mouse through the injection, among split up quality stem cell gradually because and in building under cooperation of blood cell, can't last requirement to mouse disease the blood vessel endothelial cell hyperplasias of positions large. Finally, big the intersection of mouse and which is short of blood lower extremities capillary grow notably, side prop up blood flow volume increase, ischemic symptom is relieved. In order to make the bone marrow monocyte reach the disease position directly, reduce the risk dying in its way, the researcher tests separately cells such as the injection,etc. transport the law in the injection, artery in the skin, and confirm its curative effect through the angiography after injecting 10 days, 20 days and 30 days. The experimental result reveals, half of the monocytic total amount of bone marrow that will be needed to transplant passes the injection in the skin, implement the injection in the artery to the remaining half, can make the disease position form " the new blood vessel produce the base " comparatively fast and for a long time ,Relatively realize the best transplantation result. This kind of cell transplants the method and already obtains Russia's federal patent to authorize. The gram of inferior knob of Slay Ma of the expert who participates in this research points out, the essence of this kind of stem cell's treatment is to let the ischemic disease position implement the by-pass surgery of blood vessel by oneself, the progress that this project makes can be promoted and treated the research of the human vascular disease with biotechnology.

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