Body cells are induced and can be turned into liver cells
It is reported ' Reporter Hu DeRong) Chinese Academy of Sciences the intersection of Shanghai and the intersection of life and the intersection of research institute and biochemistry and the intersection of cell and biological research institute favour profit good for whom research group finish recently liver cell study about person who transform, have proved the body cells beyond the liver can be induced to turn into liver cells directly for the first time in the world. Thesis of this research is issued on international top academic publication Nature online on May 12. Relevant experts think, this research establishes the foundation that the body cells since from the patient in future induced obtaining liver cells. The profit of favor is strong in the research group on the premise of studying and is induced and transformed, inhibited the old and feeble mechanism of cell, change over to 3 transcription factors, succeed in transforming the fibrous cells on the little mouse tail into liver cells. The cell have with leather the intersection of cell and shape, gene expression table at the internal the intersection of liver and similar cell, also have a function of liver cells, such as accumulating, transshipment, medicine supersession and indole green absorption of the lipoprotein of low density of acetylation of glycogen of liver,etc.. In should under king have assistance of seminar more happy, favour profit good for research group the intersection of liver and cell transplant, give simulation human the intersection of hydroxyphenylaminopropionic acid and the intersection of supersession and defective little mouse of disease person who transform, its hyperplasia in accepting the liver of little mouse transplanted, made the little mouse which was close to the death survive finally, indexes such as his President's bilirubin, transaminase, hydroxyphenylaminopropionic acid,etc. obviously take a favorable turn.
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