Body cells " Turn into the body " The multi-functional stem cell induces the mechanism to announce tentatively

Body cells " Turn into the body " The multi-functional stem cell induces the mechanism to announce tentatively
Beijing, June 18 (Xinhua) ' Reporter Wu JingJing) One of the international stem-cell research focuses in the past 4 years - -Induce multi-functional stem cell's mechanism to study and obtain breakthrough progress. A research of the scientist of our country, has announced body cells against transferring to starting the mechanism of multi-functional stem cell, have directive significance in inducing completion and disease treatment of multi-functional stem cell's technology. The intersection of Chinese Academy of Sciences and the intersection of Guangzhou and biological medicine and this research results that researcher waits for someone, minister of end, Pei, research institute of health, issue on the academic periodical " cell stem cell " of international authority published on June 18 Beijing time. This magazine issued the comment of Harvard University Dr. Hou Klinger at the same time, think this job has announced one and filled quality - key effect in inducing the multi-functional stem cell to form of transfer process of epidermis cell, revealed cell heavy programming, course and canceration course of development are surprising and similar at the same time. Multi-functional stem cell can orientation is divided into various cells, organizations, organs,etc., also known as the omnipotent cell. Stem-cell research is a hot field with scientific life next life in recent years, it is significant while treating, organizing organ transplant and gene therapy in cells, developing screening and such fields as drug effect, new gene are explored and assessed with genetic function analysis, toxicity will have important influence in new medicine. In 1981, British scientist isolated embryo's stem cell from the little mouse and trained outside the body, trained and did not succeed outside the body of people's embryo stem cell until 1998. But because of religion, culture, ethics, etc., there has been great break-through in its study and application. 2006, Japanese scholar stretch, fill in the world becoming body obtain the multi-functional stem cell of induction whose function is similar to embryo's stem cell in the cell from little mouse for the first time in the mountain ' Namely iPS cells) ,Have started the new page of stem-cell research. Induce multi-functional the intersection of stem cell and technology have extensive application prospect, but its induce mechanism to be unidentified inducing efficiency bow problem, become, perplex the intersection of scientist and the intersection of application and bottleneck of technology this. The biological medicine in Guangzhou of Chinese Academy of Sciences and research institute of the health take the lead in inducing multi-functional stem-cell research at home. The research group that Pei DuanQing led focuses on the induction mechanism of the multi-functional stem cell and induces two key problems of efficiency in recent years, have carried on a large number of work, has made a series of achievement. After finding last year vitamin C can induce the multi-functional stem cell with higher speed, another of research results of Pei DuanQing group has announced that form starting the mechanism of heavy programming course which induce the multi-functional stem cell. "We find 4 transcription factors which participate in heavy programming pass the cooperative effect, the ones that made in the experiment had lost the original cell characteristic as fibrous cells, ' change body ' into the cells with epidermis cell characteristic, this course has been opened to the road to the multi-functional stem cell. " Pei DuanQing says.

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