Thursday, May 3, 2012

People and pig influenza virus reset the phenomenon to increase in pig's body

People and pig influenza virus reset the phenomenon to increase in pig's body
It is reported ' Reporter Li TianShu) The pig is that influenza virus steps the intermediate host travelling among kind, our country makes the new development in aetiology research of pig's influenza. The pathogenic microbe of the Chinese Academy of Sciences and researcher's research of key laboratory of the immunology show, a group of infection not finding H5N1 bird flu virus of pig of our country, but the virus of H3N2, H1N1, H9N2 is infected exists, and messenger's influenza virus and pig's rearrangement phenomenon in pig's body of influenza virus increase to some extent in recent years. The relevant thesis is issued on " clinical virology magazine " published recently. Big human influenza 3 times that broke out in the 20th century is both closely related to pig's influenza, its popular one all reset mutation through the gene in pig's body. The poisonous one of prevalence of this first type H1N1 influenza is by pig's influenza, people's influenza and 3 kinds of genetic fragments of influenza virus of bird flu reset the new variation poison one got by the gene, the pig will give play to the role of important intermediate host in the forming process of the poison one most probably if the pig makes a variation here. Researchers monitor serology to the pig farms of Fujian Province 9 areas between 2004 and 2007, in 1407 copies of serum, undetected to H5N1 inferior type positive antibody, prove H5N1 virus has not spread in the pig group extensively, but infect the incident to happen in some areas accidentally. But researcher find the intersection of pig and group, area of Fujian, infect H1N1 and the intersection of H3N2 and getting inferior very much general influenza virus, H1N1 positive rate is 47%, H3N2 positive rate is 28%, among them H1N1 has comparative advantage, the positive rate for two years in succession is about 50%. In addition, though H9N2 positive rate is not high, consider its important public health meaning, its popular situation still merits attention. It is reported, H3N2 inferior type influenza virus mainly exists in crowd and pig group, quite popular worldwide since 1968. Researchers separate 5 H3N2 inferior type person's influenza virus and 4 H3N2 inferior type pig's influenza virus in the pig group, 5 every genetic fragments of H3N2 inferior type person's influenza virus come from H3N2 inferior type people's influenza virus in the same period, and 4 H3N2 inferior type pig's influenza virus come from previous H3N2 inferior type people's influenza virus besides specific poisonous one. This result indicates pig's influenza virus evolves a little slower than people influenza virus, the ones that will cause influenza virus in close contact of people and pig will transmit and produce the poisonous one of recombination influenza of the new genotype while stepping kind. Researchers point out, it is becoming more complicated for the above-mentioned research to show pig's influenza virus in the pig herd of our country, need to set up long-term effective aetiology monitoring system urgently, in order to grasp prevalence and hereditary variation situation of pig's influenza virus. This research set up science for our country the effective early warning system of disease has established the important theoretical foundation.

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